The nerve regrowth and protection tubes are intended for the repair of peripheral nerve lesions in patients suffering from total nerve rupture.
Two versions are available:
/ REAXON® NERVE GUIDE
Assists nerve regrowth when a direct suture is not possible (for sutures with a loss of substance of up to 26 mm)
/ REAXON® DIRECT
Enables protection when there is little or no loss of matter
1 Croisier F, Jérôme C. Chitosan-based biomaterials for tissue engineering. European Polymer Journal. avr 2013;49(4):780‑92.
2 Haastert-Talini et al. Chitosan tubes of varying degrees of acetylation for bridging peripheral nerve defects. Biomaterials 2013; 34: 9886-9904.
3 The biocompatibility of Reaxon® Nerve Guide has been proven in accordance with the ISO 10993 standards.
4 Marcol et al. Reduction of post-traumatic neuroma and epineural scar formation in rat sciatic nerve by application of microcrystallic chitosan. Microsurgery 2011; 31: 642-649.
5 Rabea et al. Chitosan as antimicrobial agent: application and mode of action. Biomacromolecules 2003; 4: 1457-1465.
6 Oliveira et al. Chitosan drives anti-inflammatory macrophage polarisation and pro-inflammatory denditric cell stimulation. Eur Cell Mater 2012; 24: 136-52
7 Yuan et al. The interaction of Schwann cells with chitosan membranes and fibers in vitro. Biomaterials 2004; 25: 4273-4278
8 Freier et al. Chitin-based tubes for tissue engineering in the nervous system. Biomaterials 2005; 26: 6424-6432.